EGFR - FAR1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EGFR	ENSG00000146648	glioma NSCLC	AFATINIB CETUXIMAB ERLOTINIB GEFITINIB LAPATINIB PANITUMUMAB VANDETANIB	glycoprotein binding chromatin binding double-stranded DNA binding MAP kinase kinase kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity epidermal growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity integrin binding protein binding calmodulin binding ATP binding enzyme binding protein kinase binding protein phosphatase binding ubiquitin protein ligase binding identical protein binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity epidermal growth factor binding actin filament binding cadherin binding involved in cell-cell adhesion nitric-oxide synthase regulator activity protein domain specific binding	let-23 (C. elegans) Egfr (D. melanogaster)
FAR1	ENSG00000197601	No diseases in record	No drugs in record	3-chloroallyl aldehyde dehydrogenase activity oxidoreductase activity 1-hydroxy-2-naphthaldehyde dehydrogenase activity cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity 2-carboxybenzaldehyde dehydrogenase activity trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity benzaldehyde dehydrogenase activity 2-naphthaldehyde dehydrogenase activity 1-naphthaldehyde dehydrogenase activity 4-hydroxymethylsalicyaldehyde dehydrogenase activity 3-methylsalicylaldehyde dehydrogenase activity oxoglutarate dehydrogenase [NAD(P)+] activity oxoglutarate dehydrogenase (NAD+) activity pyruvate dehydrogenase (NAD+) activity citronellal dehydrogenase activity geranial dehydrogenase activity N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity glyceraldehyde dehydrogenase (NADP) activity N-acetyl-gamma-aminoadipyl-phosphate reductase activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity 2,5-dioxovalerate dehydrogenase (NAD+) activity long-chain-fatty-acyl-CoA reductase activity medium-chain-aldehyde dehydrogenase activity fatty-acyl-CoA reductase (alcohol-forming) activity protein kinase inhibitor activity zinc ion binding metal ion binding cyclin-dependent protein serine/threonine kinase inhibitor activity	CG8306 (D. melanogaster)