FYN - EGFR

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FYN	ENSG00000010810	No diseases in record	DASATINIB MITOXANTRONE	G-protein coupled receptor binding glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding tubulin binding enzyme binding T cell receptor binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding ion channel binding metal ion binding ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity peptide hormone receptor binding growth factor receptor binding	Src64B (D. melanogaster)
EGFR	ENSG00000146648	glioma NSCLC	AFATINIB CETUXIMAB ERLOTINIB GEFITINIB LAPATINIB PANITUMUMAB VANDETANIB	glycoprotein binding chromatin binding double-stranded DNA binding MAP kinase kinase kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity epidermal growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity integrin binding protein binding calmodulin binding ATP binding enzyme binding protein kinase binding protein phosphatase binding ubiquitin protein ligase binding identical protein binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity epidermal growth factor binding actin filament binding cadherin binding involved in cell-cell adhesion nitric-oxide synthase regulator activity protein domain specific binding	let-23 (C. elegans) Egfr (D. melanogaster)