EGFR - TAF9

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EGFR	ENSG00000146648	glioma NSCLC	AFATINIB CETUXIMAB ERLOTINIB GEFITINIB LAPATINIB PANITUMUMAB VANDETANIB	glycoprotein binding chromatin binding double-stranded DNA binding MAP kinase kinase kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity epidermal growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity integrin binding protein binding calmodulin binding ATP binding enzyme binding protein kinase binding protein phosphatase binding ubiquitin protein ligase binding identical protein binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity epidermal growth factor binding actin filament binding cadherin binding involved in cell-cell adhesion nitric-oxide synthase regulator activity protein domain specific binding	let-23 (C. elegans) Egfr (D. melanogaster)
TAF9	ENSG00000273841	No diseases in record	No drugs in record	p53 binding DNA binding transcription coactivator activity protein binding activating transcription factor binding transcription regulatory region DNA binding protein heterodimerization activity ATPase binding C2H2 zinc finger domain binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly histone acetyltransferase activity transcription factor binding protein complex scaffold activity chromatin binding transcription factor activity, core RNA polymerase II binding	TAF9 (S. cerevisiae) taf-9 (C. elegans) e(y)1 (D. melanogaster)