SMARCE1 - TOP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMARCE1	ENSG00000073584	meningioma	No drugs in record	chromatin binding transcription coactivator activity RNA binding protein binding N-acetyltransferase activity ligand-dependent nuclear receptor binding protein N-terminus binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	swsn-3 (C. elegans)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)