ADAM10 - WRN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ADAM10	ENSG00000137845	No diseases in record	No drugs in record	endopeptidase activity metalloendopeptidase activity receptor binding integrin binding protein binding metallopeptidase activity SH3 domain binding protein kinase binding protein homodimerization activity metal ion binding	sup-17 (C. elegans)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)