ARX - WRN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARX	ENSG00000004848	No diseases in record	No drugs in record	RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding chromatin binding nucleic acid binding	hbn (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)