WRN - ERCC4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)
ERCC4	ENSG00000175595	skin basal cell skin squamous cell melanoma	No drugs in record	single-stranded DNA endodeoxyribonuclease activity TFIID-class transcription factor binding damaged DNA binding single-stranded DNA binding endodeoxyribonuclease activity protein binding protein C-terminus binding protein N-terminus binding	RAD1 (S. cerevisiae) xpf-1 (C. elegans) mei-9 (D. melanogaster)