CFTR - PRMT5

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CFTR	ENSG00000001626	No diseases in record	CROFELEMER IVACAFTOR LUMACAFTOR	chloride channel activity intracellular ATPase-gated chloride channel activity protein binding ATP binding bicarbonate transmembrane transporter activity chloride transmembrane transporter activity chloride channel regulator activity chloride channel inhibitor activity enzyme binding PDZ domain binding ATPase-coupled anion transmembrane transporter activity	BPT1 (S. cerevisiae)
PRMT5	ENSG00000100462	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding transcription corepressor activity protein binding methyltransferase activity methyl-CpG binding histone-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity protein complex binding protein-arginine omega-N symmetric methyltransferase activity ribonucleoprotein complex binding histone methyltransferase activity (H4-R3 specific) protein heterodimerization activity	HSL7 (S. cerevisiae) prmt-5 (C. elegans) csul (D. melanogaster)