CBS - SMAD2

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBS	ENSG00000160200	No diseases in record	No drugs in record	cystathionine beta-synthase activity cysteine synthase activity protein binding oxygen binding enzyme binding heme binding pyridoxal phosphate binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity metal ion binding nitrite reductase (NO-forming) activity carbon monoxide binding nitric oxide binding modified amino acid binding S-adenosyl-L-methionine binding Rab GTPase binding ADP-ribosylation factor binding	CYS4 (S. cerevisiae) Cbs (D. melanogaster)
SMAD2	ENSG00000175387	colorectal carcinoma hepatocellular carcinoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding transcription factor binding phosphatase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ubiquitin protein ligase binding activating transcription factor binding type I transforming growth factor beta receptor binding enhancer binding protein homodimerization activity SMAD binding metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding R-SMAD binding DNA binding	sma-3 (C. elegans) sma-2 (C. elegans)