PTEN - FOXO4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PTEN	ENSG00000283094	glioma prostate endometrial harmartoma	No drugs in record	magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity non-membrane spanning protein tyrosine phosphatase activity actin binding	daf-18 (C. elegans) Pten (D. melanogaster)
FOXO4	ENSG00000184481	AL soft tissue sarcoma	No drugs in record	RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding transcription factor binding enzyme binding identical protein binding sequence-specific DNA binding promoter-specific chromatin binding	HCM1 (S. cerevisiae) daf-16 (C. elegans) foxo (D. melanogaster)