CDKN1B - SMAD4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDKN1B	ENSG00000111276	breast small intestine neuroendocrine tumours pituitary parathyroid	No drugs in record	cyclin-dependent protein serine/threonine kinase inhibitor activity transforming growth factor beta receptor, cytoplasmic mediator activity protein binding protein phosphatase binding Hsp70 protein binding protein complex binding chaperone binding cysteine-type endopeptidase activator activity involved in apoptotic process	No GO terms in record
SMAD4	ENSG00000141646	colorectal pancreatic small intestine gastrointestinal polyp	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding chromatin binding protein binding collagen binding transforming growth factor beta receptor, common-partner cytoplasmic mediator activity identical protein binding protein homodimerization activity transcription regulatory region DNA binding metal ion binding protein heterodimerization activity I-SMAD binding R-SMAD binding transcription factor activity, protein binding DNA binding transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding	Med (D. melanogaster)