PIKFYVE - RAF1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIKFYVE	ENSG00000115020	No diseases in record	No drugs in record	1-phosphatidylinositol-3-phosphate 5-kinase activity protein binding ATP binding zinc ion binding 1-phosphatidylinositol-4-phosphate 5-kinase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	FAB1 (S. cerevisiae) ppk-3 (C. elegans)
RAF1	ENSG00000132155	pilocytic astrocytoma prostate	REGORAFENIB SORAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding kinase activity enzyme binding mitogen-activated protein kinase kinase binding identical protein binding metal ion binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)