CASP8 - MAPK12

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
MAPK12	ENSG00000188130	No diseases in record	No drugs in record	magnesium ion binding protein serine/threonine kinase activity MAP kinase activity protein binding ATP binding	HOG1 (S. cerevisiae) pmk-1 (C. elegans) p38b (D. melanogaster) p38a (D. melanogaster) p38c (D. melanogaster)