SLC11A2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SLC11A2	ENSG00000110911	No diseases in record	No drugs in record	copper ion transmembrane transporter activity iron ion transmembrane transporter activity manganese ion transmembrane transporter activity protein binding hydrogen ion transmembrane transporter activity cadmium ion transmembrane transporter activity cobalt ion transmembrane transporter activity ferrous iron transmembrane transporter activity lead ion transmembrane transporter activity solute:proton symporter activity ferrous iron uptake transmembrane transporter activity cadmium ion binding transition metal ion transmembrane transporter activity	SMF1 (S. cerevisiae) SMF2 (S. cerevisiae) SMF3 (S. cerevisiae) Mvl (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)