ATP7A - SMAD2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ATP7A	ENSG00000165240	No diseases in record	No drugs in record	copper-exporting ATPase activity copper ion transmembrane transporter activity copper ion binding protein binding ATP binding superoxide dismutase copper chaperone activity copper-dependent protein binding	CCC2 (S. cerevisiae) cua-1 (C. elegans) ATP7 (D. melanogaster)
SMAD2	ENSG00000175387	colorectal carcinoma hepatocellular carcinoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding transcription factor binding phosphatase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity ubiquitin protein ligase binding activating transcription factor binding type I transforming growth factor beta receptor binding enhancer binding protein homodimerization activity SMAD binding metal ion binding protein heterodimerization activity co-SMAD binding I-SMAD binding R-SMAD binding DNA binding	sma-3 (C. elegans) sma-2 (C. elegans)