HIP1 - EGFR

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
HIP1 ENSG00000127946 CMML
NSCLC

No drugs in record

epidermal growth factor receptor binding
structural constituent of cytoskeleton
protein binding
clathrin binding
clathrin light chain binding
phosphatidylinositol-3-phosphate binding
phosphatidylinositol binding
glutamate receptor binding
AP-2 adaptor complex binding
clathrin adaptor activity
protein homodimerization activity
phosphatidylinositol-3,4-bisphosphate binding
protein heterodimerization activity
actin filament binding
phosphatidylinositol-3,5-bisphosphate binding
phosphatidylinositol-4,5-bisphosphate binding
high-affinity L-histidine transmembrane transporter activity
antiporter activity
actin binding
phospholipid binding
transcription corepressor activity
SLA2 (S. cerevisiae)
Hip1 (D. melanogaster)
EGFR ENSG00000146648 glioma
NSCLC
AFATINIB
CETUXIMAB
ERLOTINIB
GEFITINIB
LAPATINIB
PANITUMUMAB
VANDETANIB
glycoprotein binding
chromatin binding
double-stranded DNA binding
MAP kinase kinase kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
epidermal growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
integrin binding
protein binding
calmodulin binding
ATP binding
enzyme binding
protein kinase binding
protein phosphatase binding
ubiquitin protein ligase binding
identical protein binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
epidermal growth factor binding
actin filament binding
cadherin binding involved in cell-cell adhesion
nitric-oxide synthase regulator activity
protein domain specific binding
let-23 (C. elegans)
Egfr (D. melanogaster)