PTEN - WT1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PTEN	ENSG00000283094	glioma prostate endometrial harmartoma	No drugs in record	magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity non-membrane spanning protein tyrosine phosphatase activity actin binding	daf-18 (C. elegans) Pten (D. melanogaster)
WT1	ENSG00000184937	Wilms tumour desmoplastic small round cell tumour	No drugs in record	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding RNA binding protein binding zinc ion binding double-stranded methylated DNA binding sequence-specific DNA binding transcription regulatory region DNA binding hemi-methylated DNA-binding C2H2 zinc finger domain binding	MIG1 (S. cerevisiae) MIG2 (S. cerevisiae) MIG3 (S. cerevisiae)