PPARG - CDK4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PPARG	ENSG00000132170	follicular thyroid	BALSALAZID MESALAMINE OLSALAZINE PIOGLITAZONE ROSIGLITAZONE TROGLITAZONE	core promoter sequence-specific DNA binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding prostaglandin receptor activity protein binding transcription factor binding drug binding zinc ion binding enzyme binding protein phosphatase binding estrogen receptor binding ligand-dependent nuclear receptor transcription coactivator activity activating transcription factor binding identical protein binding transcription regulatory region DNA binding retinoid X receptor binding arachidonic acid binding alpha-actinin binding sequence-specific DNA binding	sex-1 (C. elegans)
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)