CDK4 - ERCC3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)
ERCC3	ENSG00000163161	skin basal cell skin squamous cell melanoma	No drugs in record	DNA binding damaged DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding GTP binding protein C-terminus binding transcription factor binding ATPase activity dATP binding peptide binding 3'-5' DNA helicase activity protein N-terminus binding protein kinase activity DNA-dependent ATPase activity RNA polymerase II carboxy-terminal domain kinase activity	SSL2 (S. cerevisiae) xpb-1 (C. elegans) hay (D. melanogaster)