CDK4 - HSF1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDK4	ENSG00000135446	melanoma	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin-dependent protein serine/threonine kinase regulator activity cyclin binding protein complex binding protein serine/threonine kinase activity	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)
HSF1	ENSG00000185122	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein kinase binding heat shock protein binding identical protein binding STAT family protein binding sequence-specific single stranded DNA binding promoter-specific chromatin binding sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	HSF1 (S. cerevisiae) hsf-1 (C. elegans)