PPP1CA - TOP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PPP1CA	ENSG00000172531	No diseases in record	No drugs in record	phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein binding protein phosphatase 1 binding phosphatase activity protein complex binding ribonucleoprotein complex binding metal ion binding	GLC7 (S. cerevisiae) Pp1-87B (D. melanogaster) flw (D. melanogaster) Pp1-13C (D. melanogaster) Pp1alpha-96A (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)