HDAC1 - NPM1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC1	ENSG00000116478	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	transcription regulatory region sequence-specific DNA binding core promoter binding RNA polymerase II transcription factor binding RNA polymerase II repressing transcription factor binding RNA polymerase II transcription corepressor activity transcription factor activity, sequence-specific DNA binding histone deacetylase activity protein binding transcription factor binding deacetylase activity enzyme binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity activating transcription factor binding histone deacetylase binding transcription regulatory region DNA binding protein N-terminus binding NF-kappaB binding repressing transcription factor binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	RPD3 (S. cerevisiae) hda-1 (C. elegans) hda-3 (C. elegans)
NPM1	ENSG00000181163	NHL APL AML	No drugs in record	transcription coactivator activity RNA binding protein kinase inhibitor activity protein binding protein kinase binding Tat protein binding histone binding protein homodimerization activity ribosomal large subunit binding ribosomal small subunit binding protein heterodimerization activity NF-kappaB binding unfolded protein binding	No GO terms in record