TOP1 - LCMT1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)
LCMT1	ENSG00000205629	No diseases in record	No drugs in record	protein C-terminal carboxyl O-methyltransferase activity protein binding S-adenosylmethionine-dependent methyltransferase activity protein C-terminal leucine carboxyl O-methyltransferase activity	PPM2 (S. cerevisiae) B0285.4 (C. elegans)