TOP1MT - BLM

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP1MT	ENSG00000184428	No diseases in record	IRINOTECAN TOPOTECAN	DNA binding DNA topoisomerase type I activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)
BLM	ENSG00000197299	leukaemia lymphoma skin squamous cell other tumour types	No drugs in record	bubble DNA binding p53 binding single-stranded DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding ATP-dependent helicase activity four-way junction helicase activity ATPase activity annealing helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding DNA helicase activity DNA-dependent ATPase activity Y-form DNA binding	SGS1 (S. cerevisiae) him-6 (C. elegans) Blm (D. melanogaster)