RAF1 - VAV3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAF1	ENSG00000132155	pilocytic astrocytoma prostate	REGORAFENIB SORAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding kinase activity enzyme binding mitogen-activated protein kinase kinase binding identical protein binding metal ion binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
VAV3	ENSG00000134215	No diseases in record	No drugs in record	SH3/SH2 adaptor activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity epidermal growth factor receptor binding protein binding Rac guanyl-nucleotide exchange factor activity metal ion binding	CDC24 (S. cerevisiae)