SMAD4 - IQGAP2

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SMAD4 ENSG00000141646 colorectal
pancreatic
small intestine
gastrointestinal polyp

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
chromatin binding
protein binding
collagen binding
transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
identical protein binding
protein homodimerization activity
transcription regulatory region DNA binding
metal ion binding
protein heterodimerization activity
I-SMAD binding
R-SMAD binding
transcription factor activity, protein binding
DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
Med (D. melanogaster)
IQGAP2 ENSG00000145703

No diseases in record

No drugs in record

actin binding
GTPase inhibitor activity
calmodulin binding
phosphatidylinositol-3,4,5-trisphosphate binding
Rho GTPase binding
Rac GTPase binding
actin filament binding
Arp2/3 complex binding
IQG1 (S. cerevisiae)