CDC27 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDC27	ENSG00000004897	No diseases in record	No drugs in record	protein binding protein phosphatase binding ubiquitin-protein transferase activity ubiquitin protein ligase activity DNA-directed DNA polymerase activity 3'-5' exonuclease activity	CDC27 (S. cerevisiae) Cdc27 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)