IKBKB - TOP2A

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IKBKB	ENSG00000104365	SMZL	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein binding ATP binding IkappaB kinase activity protein kinase binding protein homodimerization activity protein heterodimerization activity scaffold protein binding	ATG1 (S. cerevisiae)
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)