TOP2A - AR

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
AR	ENSG00000169083	prostate	BICALUTAMIDE DANAZOL DROMOSTANOLONE PROPIONATE ENZALUTAMIDE ETHYLESTRENOL FLUOXYMESTERONE FLUTAMIDE METHYLTESTOSTERONE NANDROLONE DECANOATE NANDROLONE PHENPROPIONATE NILUTAMIDE OXANDROLONE OXYMETHOLONE STANOZOLOL TESTOSTERONE TESTOSTERONE CYPIONATE TESTOSTERONE ENANTHATE TESTOSTERONE PROPIONATE TESTOSTERONE UNDECANOATE	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding androgen receptor activity receptor binding steroid binding androgen binding protein binding beta-catenin binding transcription factor binding zinc ion binding enzyme binding transcription regulatory region DNA binding protein dimerization activity ATPase binding POU domain binding	No GO terms in record