TOP2A - TIAM1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
TIAM1	ENSG00000156299	No diseases in record	No drugs in record	signal transducer activity, downstream of receptor guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding microtubule binding lipid binding kinase binding Rac guanyl-nucleotide exchange factor activity receptor tyrosine kinase binding Rac GTPase binding	No GO terms in record