TOP2A - PPME1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
PPME1	ENSG00000214517	No diseases in record	No drugs in record	protein phosphatase inhibitor activity protein phosphatase regulator activity protein kinase binding protein phosphatase binding protein phosphatase 2A binding protein C-terminal methylesterase activity cadherin binding involved in cell-cell adhesion	PPE1 (S. cerevisiae) B0464.9 (C. elegans) CG5068 (D. melanogaster)