RAF1 - USP8

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAF1	ENSG00000132155	pilocytic astrocytoma prostate	REGORAFENIB SORAFENIB	protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding kinase activity enzyme binding mitogen-activated protein kinase kinase binding identical protein binding metal ion binding protein heterodimerization activity small GTPase binding	lin-45 (C. elegans)
USP8	ENSG00000138592	corticotroph adenoma	No drugs in record	cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity protein binding SH3 domain binding cadherin binding involved in cell-cell adhesion	DOA4 (S. cerevisiae) UBP5 (S. cerevisiae)