TOP2A - MUS81

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
TOP2A ENSG00000131747

No diseases in record

DAUNORUBICIN
DOXORUBICIN
EPIRUBICIN
ETOPOSIDE
ETOPOSIDE PHOSPHATE
IDARUBICIN
MITOXANTRONE
PODOFILOX
TENIPOSIDE
VALRUBICIN
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
MUS81 ENSG00000172732

No diseases in record

No drugs in record

DNA binding
endodeoxyribonuclease activity
protein binding
metal ion binding
3'-flap endonuclease activity
crossover junction endodeoxyribonuclease activity
nuclease activity
endonuclease activity
enzyme inhibitor activity
hydrolase activity
MUS81 (S. cerevisiae)
mus81 (D. melanogaster)