MCM6 - EGFR

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MCM6	ENSG00000076003	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding identical protein binding ATP-dependent DNA helicase activity ATP-dependent four-way junction helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity DNA replication origin binding DNA binding ATP-dependent 3'-5' DNA helicase activity DNA helicase activity helicase activity single-stranded DNA-dependent ATPase activity nucleotide binding hydrolase activity 3'-5' DNA helicase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity	MCM6 (S. cerevisiae)
EGFR	ENSG00000146648	glioma NSCLC	AFATINIB CETUXIMAB ERLOTINIB GEFITINIB LAPATINIB PANITUMUMAB VANDETANIB	glycoprotein binding chromatin binding double-stranded DNA binding MAP kinase kinase kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity transmembrane signaling receptor activity epidermal growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity integrin binding protein binding calmodulin binding ATP binding enzyme binding protein kinase binding protein phosphatase binding ubiquitin protein ligase binding identical protein binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity protein heterodimerization activity epidermal growth factor binding actin filament binding cadherin binding involved in cell-cell adhesion nitric-oxide synthase regulator activity protein domain specific binding	let-23 (C. elegans) Egfr (D. melanogaster)