CASP8 - PPM1D

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP8	ENSG00000064012	hepatocellular oral squamous cell breast	No drugs in record	cysteine-type endopeptidase activity death receptor binding tumor necrosis factor receptor binding protein binding peptidase activity cysteine-type peptidase activity ubiquitin protein ligase binding protein complex binding death effector domain binding identical protein binding scaffold protein binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
PPM1D	ENSG00000170836	glioma ovarian cancer breast cancer	No drugs in record	protein serine/threonine phosphatase activity protein binding metal ion binding mitogen-activated protein kinase binding	PTC2 (S. cerevisiae) PTC3 (S. cerevisiae)