TOP1 - TSC1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)
TSC1	ENSG00000165699	renal cell carcinoma bladder carcinoma hamartoma tuberous sclerosis tuber	No drugs in record	protein binding GTPase regulator activity GTPase activating protein binding protein N-terminus binding chaperone binding protein kinase binding kinase binding	Tsc1 (D. melanogaster)