DVL1 - MAP2K2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DVL1	ENSG00000107404	No diseases in record	No drugs in record	frizzled binding protein binding beta-catenin binding enzyme binding protein kinase binding identical protein binding Rac GTPase binding	dsh-2 (C. elegans) dsh-1 (C. elegans) mig-5 (C. elegans) dsh (D. melanogaster)
MAP2K2	ENSG00000126934	NSCLC melanoma	TRAMETINIB	protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding PDZ domain binding protein serine/threonine kinase activator activity metal ion binding scaffold protein binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)