PSMC6 - MAP2K2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PSMC6	ENSG00000100519	No diseases in record	No drugs in record	protein binding ATP binding ATPase activity TBP-class protein binding protein binding, bridging proteasome-activating ATPase activity identical protein binding	RPT4 (S. cerevisiae) rpt-4 (C. elegans) Rpt4 (D. melanogaster) Rpt4R (D. melanogaster)
MAP2K2	ENSG00000126934	NSCLC melanoma	TRAMETINIB	protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding PDZ domain binding protein serine/threonine kinase activator activity metal ion binding scaffold protein binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)