PSMC5 - MAP2K2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PSMC5	ENSG00000087191	No diseases in record	No drugs in record	transcription cofactor activity protein binding ATP binding transcription factor binding ATPase activity TBP-class protein binding thyrotropin-releasing hormone receptor binding proteasome-activating ATPase activity	RPT6 (S. cerevisiae) F56F11.4 (C. elegans) Rpt6 (D. melanogaster) Rpt6R (D. melanogaster)
MAP2K2	ENSG00000126934	NSCLC melanoma	TRAMETINIB	protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding PDZ domain binding protein serine/threonine kinase activator activity metal ion binding scaffold protein binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)