FBXW7 - MAP2K2

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
FBXW7 ENSG00000109670 colorectal
endometrial
T-ALL

No drugs in record

ubiquitin-protein transferase activity
protein binding
cyclin binding
protein binding, bridging
ubiquitin protein ligase binding
identical protein binding
phosphothreonine residue binding
ubiquitin-protein transferase activator activity
MET30 (S. cerevisiae)
sel-10 (C. elegans)
ago (D. melanogaster)
MAP2K2 ENSG00000126934 NSCLC
melanoma
TRAMETINIB
protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
PDZ domain binding
protein serine/threonine kinase activator activity
metal ion binding
scaffold protein binding
PBS2 (S. cerevisiae)
mek-2 (C. elegans)
Dsor1 (D. melanogaster)