RAN - MAP2K1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAN	ENSG00000132341	No diseases in record	No drugs in record	chromatin binding transcription coactivator activity GTPase activity protein binding GTP binding GDP binding androgen receptor binding cadherin binding involved in cell-cell adhesion protein transmembrane transporter activity pre-miRNA binding pre-miRNA transporter activity	GSP1 (S. cerevisiae) GSP2 (S. cerevisiae) Ran (D. melanogaster)
MAP2K1	ENSG00000169032	NSCLC melanoma colorectal	TRAMETINIB	protein kinase activity protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity MAP kinase kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine phosphatase activity protein binding ATP binding protein C-terminus binding protein kinase binding protein serine/threonine kinase activator activity protein N-terminus binding	PBS2 (S. cerevisiae) mek-2 (C. elegans) Dsor1 (D. melanogaster)