SMARCB1 - FEN1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMARCB1	ENSG00000099956	malignant rhabdoid	No drugs in record	RNA polymerase I CORE element sequence-specific DNA binding p53 binding DNA binding transcription coactivator activity protein binding Tat protein binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	SFH1 (S. cerevisiae) snfc-5 (C. elegans) Snr1 (D. melanogaster)
FEN1	ENSG00000168496	breast cancer	No drugs in record	magnesium ion binding DNA binding damaged DNA binding double-stranded DNA binding endonuclease activity RNA-DNA hybrid ribonuclease activity exonuclease activity protein binding double-stranded DNA exodeoxyribonuclease activity 5'-3' exonuclease activity 5'-flap endonuclease activity flap endonuclease activity nuclease activity	RAD27 (S. cerevisiae) crn-1 (C. elegans)