MCM4 - TOP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MCM4	ENSG00000104738	No diseases in record	No drugs in record	single-stranded DNA binding protein binding ATP binding ATP-dependent DNA helicase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity ATP-dependent four-way junction helicase activity DNA replication origin binding DNA binding helicase activity ATP-dependent 3'-5' DNA helicase activity DNA helicase activity nucleotide binding single-stranded DNA-dependent ATPase activity hydrolase activity single-stranded RNA binding 3'-5' DNA/RNA helicase activity ATPase activity single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity RNA helicase activity chromatin binding	MCM4 (S. cerevisiae) dpa (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)