SIRT1 - SRC

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
SRC	ENSG00000197122	colorectal cancer endometrial carcinoma	BOSUTINIB DASATINIB VANDETANIB	protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity SH3/SH2 adaptor activity protein kinase C binding receptor binding insulin receptor binding integrin binding protein binding ATP binding protein C-terminus binding kinase activity enzyme binding kinase binding heme binding estrogen receptor binding SH2 domain binding ion channel binding ephrin receptor binding phosphoprotein binding hormone receptor binding growth factor receptor binding scaffold protein binding cadherin binding involved in cell-cell adhesion	Src64B (D. melanogaster)