Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
SIRT1
|
ENSG00000096717
|
No diseases in record
|
No drugs in record
|
core promoter sequence-specific DNA binding
p53 binding
transcription corepressor activity
histone deacetylase activity
protein binding
protein C-terminus binding
transcription factor binding
NAD-dependent histone deacetylase activity
deacetylase activity
enzyme binding
protein deacetylase activity
NAD-dependent protein deacetylase activity
nuclear hormone receptor binding
histone binding
identical protein binding
HLH domain binding
bHLH transcription factor binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
mitogen-activated protein kinase binding
NAD+ binding
keratin filament binding
NAD+ ADP-ribosyltransferase activity
|
HST1 (S. cerevisiae)
SIR2 (S. cerevisiae)
sir-2.1 (C. elegans)
|
ARID1A
|
ENSG00000117713
|
clear cell ovarian carcinoma
RCC
breast
|
No drugs in record
|
DNA binding
transcription coactivator activity
protein binding
ligand-dependent nuclear receptor binding
nucleosome binding
|
let-526 (C. elegans)
osa (D. melanogaster)
|