PARP1 - CDK12

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PARP1	ENSG00000143799	No diseases in record	OLAPARIB	DNA binding DNA ligase (ATP) activity NAD+ ADP-ribosyltransferase activity protein binding transcription factor binding zinc ion binding enzyme binding protein kinase binding estrogen receptor binding identical protein binding histone deacetylase binding protein N-terminus binding NAD binding R-SMAD binding	Parp (D. melanogaster)
CDK12	ENSG00000167258	serous ovarian	No drugs in record	protein kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity cyclin binding transcription factor binding transcription regulatory region DNA binding	CTK1 (S. cerevisiae) cdk-12 (C. elegans) Cdk12 (D. melanogaster)