ROR1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ROR1	ENSG00000185483	No diseases in record	No drugs in record	transmembrane receptor protein tyrosine kinase activity protein binding ATP binding Wnt-protein binding coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	cam-1 (C. elegans)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)