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MYC - MAP2K1
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
MYC
ENSG00000136997
Burkitt lymphoma
amplified in other cancers
B-CLL
No drugs in record
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
protein complex binding
protein dimerization activity
repressing transcription factor binding
E-box binding
No GO terms in record
MAP2K1
ENSG00000169032
NSCLC
melanoma
colorectal
TRAMETINIB
protein kinase activity
protein serine/threonine kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
MAP kinase kinase activity
protein serine/threonine/tyrosine kinase activity
protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine phosphatase activity
protein binding
ATP binding
protein C-terminus binding
protein kinase binding
protein serine/threonine kinase activator activity
protein N-terminus binding
PBS2 (S. cerevisiae)
mek-2 (C. elegans)
Dsor1 (D. melanogaster)