RNF40 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RNF40	ENSG00000103549	No diseases in record	No drugs in record	mRNA 3'-UTR binding protein binding zinc ion binding syntaxin-1 binding ubiquitin conjugating enzyme binding ubiquitin protein ligase binding protein complex binding protein homodimerization activity ubiquitin-protein transferase activity	BRE1 (S. cerevisiae) rfp-1 (C. elegans) Bre1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)