HMGA1 - LCK

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HMGA1	ENSG00000137309	microfollicular thyroid adenoma various benign mesenchymal tumours	No drugs in record	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding DNA binding AT DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding enzyme binding ligand-dependent nuclear receptor transcription coactivator activity retinoic acid receptor binding peroxisome proliferator activated receptor binding retinoid X receptor binding	No GO terms in record
LCK	ENSG00000182866	T-ALL	DASATINIB PAZOPANIB	glycoprotein binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity protein binding ATP binding protein C-terminus binding kinase activity protein kinase binding protein phosphatase binding SH2 domain binding CD4 receptor binding CD8 receptor binding identical protein binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity ATPase binding	Src64B (D. melanogaster)